| Chloroquine diphosphate Basic information | |
| Product Name: | Chloroquine diphosphate |
| Synonyms: | 7-chloro-4-((4’-diethylamino-1-methylbutyl)amino)quinolinediphosphate;7-chloro-4-(4-diethylamino-1-methyl-butylamino)-quinolindiphosphate;alermine;aralendiphosphate;chingaminphosphate;chloroquindiphosphate;chloroquine bis;chloroquinebis(phosphate) |
| CAS: | 50-63-5 |
| MF: | C18H32ClN3O8P2 |
| MW: | 515.86 |
| EINECS: | 200-055-2 |
| Product Categories: | API;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Miscellaneous Enzyme;ARALEN;Inhibitors |
| Mol File: | 50-63-5.mol |
| Introduction | Chloroquine phosphate belongs to 4-aminoquinoline antimalarial drugs, which can inhibit the nucleic acid synthesis of plasmodium schizozoites, interfere with the growth and reproduction of plasmodium, and effectively kill plasmodium red endozoites. |
| Application | Chloroquine phosphate can be used to treat chloroquine-sensitive plasmodium falciparum plasmodium vivax and plasmodium malariae, and can be used to inhibit the prevention of malaria symptoms. It can also be used to treat extra-intestinal amoeba connective tissue disease and photosensitive diseases (such as erythema sunburn). |
| Chloroquine diphosphate Chemical Properties | |
| Melting point | 200 °C (dec.)(lit.) |
| storage temp. | Desiccate at RT |
| pka | pKa 8.10(H2O t = 20 c = 0.0025) (Uncertain) |
| solubility | H2O: 50 mg/mL, clear |
| form | solid |
| pH | pH(100g/l, 25℃) : 3.8～4.3 |
| Water Solubility | Soluble in water |
| Merck | 14,2163 |
| BRN | 4223142 |
| InChIKey | QKICWELGRMTQCR-UHFFFAOYSA-N |
