| Azithromycin Basic information | |
| Product Name: | Azithromycin |
| Synonyms: | -l-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamet;xz405;AZYTHROMYCIN;Azithromycin CP2000 USP24;AZITHROMYCIN IMPURITY A6-DEMETHYLAZITHROMYCIN EP STANDARD;AZITHROMYCIN IMPURITY B3-DEOXYAZITHROMYCIN EP STANDARD;AZITHROMYCIN USP STANDARD;AZITHROMYCIN DIHYDRATE(COMPACTED) |
| CAS: | 83905-01-5 |
| MF: | C38H72N2O12 |
| MW: | 748.98 |
| EINECS: | 617-500-5 |
| Product Categories: | Antibiotics; Veterinary medicine; Macrocyclic lactam antibiotics; Microbial metabolites; Plant extracts; azithromycin |
| Mol File: | 83905-01-5.mol |
| Introduction | Azithromycin is an antibiotic widely used in clinical practice. It has the advantages of wide antibacterial spectrum, little stimulation to gastrointestinal tract and fast oral absorption. |
| Application | Antibiotics are used for various infections caused by sensitive bacteria, such as respiratory system infections, skin and soft tissue infections.
Macrolide class antibiotic, 15 yuan containing nitrogen heterocyclic ring, antibacterial mechanism and erythromycin similar, but more antibacterial spectrum. It has stronger antibacterial activity against gram-positive bacteria and gram-negative bacteria such as Haemophilus influenzae, Salmonella, Escherichia coli, shigella and so on. And stable to acid, good tolerance. It has a good therapeutic effect on respiratory tract infection, skin soft tissue infection and sexually transmitted diseases caused by sensitive strains. |
| Azithromycin Chemical Properties | |
| Melting point | 113-115°C |
| alpha | D20 -37° (c = 1 in CHCl3) |
| Boiling point | 822.1±65.0 °C(Predicted) |
| density | 1.18±0.1 g/cm3(Predicted) |
| pKa | pKa 8.74 (H2O t=25 I=0.167) (Uncertain);9.45(H2O t=25 I=0.167) (Uncertain) |
| storage temp. | Store at -20°C |
| solubility | Practically insoluble in water, freely soluble in anhydrous ethanol and in methylene chloride. |
| optical activity | [α]/D 45±2°, c = 1% in ethanol |
| form | powder |
| Water Solubility | soluble |
| Stability | Stable. Incompatible with strong oxidizing agents. |
