Ursodeoxycholic acid Basic information | |
Product Name: | Ursodeoxycholic acid |
Synonyms: | Tauroursodiol; Urosodeoxycholic Acid; Ursodeoxycholic acid(micronized);; URSODIOL; UDCA |
CAS: | 128-13-2 |
MF: | C24H40O4 |
MW: | 392.57 |
EINECS: | 204-879-3 |
Product Categories: | Animal extract; Ursodeoxycholic acid; Sterols and steroids; Biochemicals; Lipid; Digestive system drugs; Pharmaceutical and biological chemicals; Chinese herbal medicine ingredients; Traditional Chinese medicine reference substance; Active pharmaceutical ingredients. Analytical standards; Plant extract; Detergent. Chemical raw materials; Daily chemicals; Inorganic substances; Target compound; General purpose biochemical reagents – lipids |
Introduction | This product is white powder; Odorless, bitter taste. It is easily soluble in ethanol and glacial acetic acid, soluble in sodium hydroxide test solution, and insoluble in chloroform. UDCA can reduce the absorption of cholesterol, and can reduce the synthesis of cholesterol and cholesterol content in bile. In addition, UDCA can also reduce the concanavalin A binding fragment, which can promote the formation of bile crystals, thereby inhibiting the formation of stones. |
Application | Gallstone dissolving medicine. It is mainly used for cholesterol gallstones that are not suitable for surgical treatment.
For the prevention and treatment of cholesterol gallstones, anionic detergent. |
Ursodeoxycholic acid Chemical Properties | |
Melting point | 203-204 °C (lit.) |
Boiling point | 437.26°C (rough estimate) |
flash point | 9℃ |
Density | 0.9985 (rough estimate) |
specific rotation | 60 º (c=2, EtOH) |
Refractive index | 60.5 ° (C=2, EtOH) |
storage condition | 2-8°C |
Solubility | ethanol: 50 mg/mL, clear |
Water solubility | practically insoluble |
form | Solid. Powder. |
color | White – almost white. |
pKa | pKa 5.04±0.04(H2O t = 25.0±0.1 I = 0.00)(Approximate) |