| SpectinoMycin Dihydrochloride Basic information | |
| Product Name: | SpectinoMycin Dihydrochloride |
| Synonyms: | SPECTINOMYCIN PENTAHYDRATE DIHYDROCHLORIDE;SPECTINOMYCIN 2HCL;SPECTINOMYCIN DIHYDROCHLORIDE PENTAHYDRATE;SPECTINOMYCIN, DIHYDROCHLORIDE, PENTAHYDRATE, STREPTOMYCES SPECIES;SPECTINOMYCIN HCL;SPECTINOMYCIN HYDROCHLORIDE;U-18409AE;M 141 |
| CAS: | 21736-83-4 |
| MF: | C14H25ClN2O7 |
| MW: | 368.81 |
| EINECS: | 244-554-3 |
| Product Categories: | Antibiotics and alkaloids; Aminoglycoside antibiotics; Small molecule inhibitors; Pharmaceutical raw materials; Food additives; Feed additive. |
| Mol File: | 21736-83-4.mol |
| Introduction | Megamycin hydrochloride is produced by Streptomyces. It is an aminoglycoside bactericidal antibiotic formed by the combination of neutral sugars and aminocyclic alcohols. It is also known as spectacular mycin. |
| Application | Spectinomycin dihydrochloride pentahydrate is an aminocylcitol antibiotic which is closely related to the aminoglycosides.Gram-positive and gram-negative Gonococcus spp. are reported to exhibit susceptibility to Spectinomycin. Studies indicate thatSpectinomycin interferes with peptidyl tRNA translocation thereby affecting protein synthesis in susceptible bacteria. Additional reports note that mutations in ribosomal proteins may prevent the binding of spectinomycin, thus potentially confering resistence to the compound. Additionally, Eschericia coli is reported to be reversibly inhibited during growth and division by Spectinomycin and that variations in bacterial sensitivity may be mediated by differences in ribosomes among different E. coli mutants. |
| SpectinoMycin Dihydrochloride Chemical Properties | |
| Melting point | 205-207° (dec) |
| alpha | D +14.8° (c = 0.42 in water) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL, clear, faintly yellow |
| color | white to off-white |
| form | powder |
| Water Solubility | Soluble in water.Soluble in water, methanol, dimethyl sulfoxide, ethanol and dimethyl formamide. |
