| Paclitaxel Basic information | |
| Product Name: | Paclitaxel |
| Synonyms: | Paclitaxel HCL; Paclitaxel(natural crude); N-BENZYL-BETA-PHENYLISOSERINE ESTER; PACLITAXEL, TAXUS BREVIFOLIA |
| CAS: | 33069-62-4 |
| MF: | C47H51NO14 |
| MW: | 853.92 |
| EINECS: | 608-826-9 |
| Product Categories: | Animal and plant anti-tumor drugs; Cancer drugs. Pharmaceutical intermediate; Chinese herbal medicine ingredients; For the class; Biomedicine; Natural source anti-tumor; Diterpenoid; In vitro research products – in vitro metabolic standards; Natural high content monomer; Plant monomer; High purity separation reagent – standard; Chemical raw materials; General reagent |
| Introduction | Taxol is a monomeric diterpenoid extracted from the bark of Taxus. It is a complex secondary metabolite and the only drug known to promote microtubule polymerization and stabilize polymerized microtubules. Precipitated needle-like crystalline or amorphous powder from methanol. |
| Application | Broad-spectrum anti-tumor plant medicine, used to treat ovarian cancer, breast cancer and other diseases. |
| Paclitaxel Chemical Properties | |
| Melting point | 213 °C (dec.)(lit.) |
| Boiling point | 774.66°C (rough estimate) |
| Density | 0.200 |
| flash point | 9℃ |
| specific rotation | D20 -49° (methanol) |
| Refractive index | -49 ° (C=1, MeOH) |
| Storage condition | 2-8°C |
| Solubility | methanol: 50 mg/mL, clear, colorless |
| form | Powder. |
| color | White |
| λmax | 227nm(MeOH)(lit.) |
| pKa | 11.90±0.20(Predicted) |
In addition, we also have semi-synthetic Paclitaxel.
