| Minoxidil Basic information | |
| Product Name: | Minoxidil |
| Synonyms: | 2, 4 – diamino – 6 – piperidinopyrimidine3 – n – oxide; 4-pyrimidinediamine,6-(1-piperidinyl)-3-oxide; – amino – 1, 2, 6 – dihydro – 1-2 – imino – 4 – hydroxy – piperidinopyrimidine; 6 – piperidino – 2, 4 – diaminopyrimidine3 – oxide; alopexil; 4 – (2, 6 – diamino – piperidin – 1 – yl) -ium pyrimidin – 1-1 – olate; alostil; lonolox |
| CAS: | 38304-91-5 |
| MF: | C9H15N5O |
| MW: | 209.25 |
| EINECS: | 253-874-2 |
| Product Categories: | Cardiovascular drugs; Antihypertensive class; Hormones; Hair care series; Circulatory system medication; Pharmaceutical intermediate; Vitamins and amino acids; Antibiotics; Small molecule inhibitor; Chemical raw materials; Raw material intermediates – apis; Hypoglycemic products; Chemical intermediates |
| Introduction | Minoxidil, also known as minoxidil, is a white or quasi-white crystalline powder, slightly soluble in water or chloroform, slightly soluble in ethanol. It can directly act on the blood vessel wall, expand small arteries, reduce peripheral resistance, and decrease blood pressure. It can also increase heart rate and cardiac output, but its antihypertensive effect is more significant and lasting than hydralazine |
| Application | Antihypertensive drugs for refractory, primary, or renal hypertension.
Used to prevent greasy alopecia and animal husbandry. |
| Minoxidil Chemical Properties | |
| Melting point | 272-274 °C (dec.) (lit.) |
| Boiling point | 348.61°C (rough estimate) |
| Density | 1.1651 (rough estimate) |
| Refractive index | 1.7610 (estimate) |
| storage condition | 2-8°C |
| Solubility | Slightly soluble in water, soluble in methanol and in propylene glycol. |
| Water solubility | Soluble in water (2.2 mg/ml), 100% ethanol (29 mg/ml), propylene glycol, acetone, DMSO (6.5 mg/ml), and methanol. |
| form | Powder |
| color | White crystal |
| pKa | 4.61(at 25℃) |
