Retinoic acid CAS 302-79-4
1.Product Name: Tretinoin 2.CAS NO: 302-79-4 3.Purity:99%min 4.Appearance: yellowish crystalline powder
| Retinoic acid Basic information | |
| Product Name: | Retinoic acid |
| Synonyms: | TRETINOIN;TRETINOIN VITAMIN A ACID;TRANS-RETINOIC ACID;VITAMIN A ACID;VITAMIN A ACID, ALL-TRANS;2,4,6,8-Nonatetraenoic acid |
| CAS: | 302-79-4 |
| MF: | C20H28O2 |
| MW: | 300.44 |
| EINECS: | 206-129-0 |
| Product Categories: | Vitamin; Biological stain; Pharmaceutical intermediate; Fluorine chemical; Skin beauty; Antineoplastic drugs; Plant extract; Anti-keratinizing drugs; Raw materials for skin application; Cosmetic raw materials – whitening agent; Skin antibacterial; Pharmaceutical and chemical industry; Hair care series; Chemical raw materials; Nutrient fortifier; Daily chemicals; Food additives; Medical raw materials; industrialization |
| Introduction | Retinol, retinaldehyde, retinol in skin care products are in the simulation of retinoic acid (retinoic acid, also known as all-trans retinoic acid) action. Yellow needle – like crystals with a similar odor to vitamin methyl acetate. |
| Application | Antikeratolytic drug.
Retinoic acid is mainly used in the treatment of psoriasis, ichthyosis, keratosis follicularis, acne, lichen flatus, verrucous epidermal nevus, subangular pustulosis, leukoplakia, pityriasis rubra fur and pityriasis facialis. In addition, it also has a certain preventive effect on skin cancer. It is used to treat acne vulgaris, especially comedones, senile, solar or medicated skin atrophy, ichthyosis, various abnormal keratosis, hyperpigmentation skin diseases and psoriasis. |
| Retinoic acid Chemical Properties | |
| Melting point | 180-181 °C (lit.) |
| Boiling point | 381.66°C (rough estimate) |
| Density | 1.0597 (rough estimate) |
| Refractive index | 1.4800 (estimate) |
| storage condition | -20°C |
| Solubility | Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). |
| Water solubility | insoluble |
| form | Powder. |
| color | Yellow needle – like crystals |
| pKa | 4.73±0.33(Predicted) |
