| Fluconazole Basic information | |
| Product Name: | Fluconazole |
| Synonyms: | 2,4-DIFLUORO-,1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYLALCOHOL;A-(2,4-DIFLUOROPHENYL)-A-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1H-1,2,4-TRIAZOL-1-ETHANOL;1h-1,2,4-triazole-1-ethanol,alpha-(2,4-difluorophenyl)-alpha-(1h-1,2,4-triazol;-1-ylmethyl)-;alpha-(2,4-difluorophenyl)-alpha-(1h-1,2,4-triazol-1-ylmethyl)-1h-1,2,4-tria;uk49858;Fluconazole,2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol |
| CAS: | 86386-73-4 |
| MF: | C13H12F2N6O |
| MW: | 306.27 |
| EINECS: | 627-806-0 |
| Product Categories: | Antipyretic and analgesic; Pharmaceutical raw materials; Medicine antibacterial; Antibiotics; Antifungal; Small molecule inhibitor; Pharmaceutical grade; Antibiotics; Disease-resistant microbial drugs; Antifungal agents; Raw materials for skin application; Agricultural raw materials; Chemical raw materials; Pharmaceutical additive; Synthetic antimicrobial agents; Pharmaceutical, pesticide and dye intermediates; Organic intermediate |
| Introduction | Fluconazole is a novel triazole antifungal agent, which has a broad spectrum antifungal effect and belongs to systemic antifungal products. It is highly selective in the inhibition of fungal cytochrome P-450 dependent enzymes, and is also a potent and specific inhibitor of fungal alcohol synthesis. White to yellowish white crystalline powder, slightly peculiar odor, bitter taste. |
| Application | Fluconazole is a fluorotriazole antifungal agent with similar antibacterial spectrum and stronger antibacterial activity than ketoconazole. It is mainly used as the raw material of fluconazole fluconazole injection.
It is mainly used for candidiasis and cryptococcosis, and is also effective against oropharyngeal Candida infections in cancer patients. |
| Fluconazole Chemical Properties | |
| Melting point | 138-140°C |
| Boiling point | 579.8±60.0 °C(Predicted) |
| Density | 1.05 |
| flash point | 9℃ |
| Storage condition | 2-8°C |
| Solubility | DMSO: 5 mg/mL |
| form | Powder. |
| color | White to off-white crystalline |
| pKa | pKa 1.76±0.1(H2O t=24 I=0.1(NaCl)) (Uncertain) |
