Florfenicol Basic information | |
Product Name: | Florfenicol |
Synonyms: | Acetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-;2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide;Aquaflor;Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide;Benzenesulfonic acid, 4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-, methyl ester, (R-(R,S));[(R-(R*,S*)]-4-[2-[(Dichloroacetyl)amino]-3-fluoro-1-hydroxypropyl]benzensulfonic acid methyl ester |
CAS: | 73231-34-2 |
MF: | C12H14Cl2FNO4S |
MW: | 358.21 |
EINECS: | 642-986-0 |
Product Categories: | Antibiotics; Food additives; API API – Immune system drugs; Feed additive; Microbial metabolites; Veterinary medicine. |
Mol File: | 73231-34-2.mol |
Introduction | Florfenicol is white crystall powder, odourless, taste bitter. This product in DMF dissolve easily in the dissolved in methanol in slightly soluble in glacial acetic acid in water or chloroform micro dissolve. Suitable for various kinds of various infections caused by sensitive bacteria. |
Application | 1) For pigs arthritis, pneumonia, atrophic rhinitis and other diseases caused by streptococcus, pneumococcal, haemophilus. 2) Auxiliary treatment of breathing and reproduction obstacle syndrome, Aujeszky’s Disease, bacterial infection caused by influenza. 3) An antibacterial. Fluorinated derivative of thiamphenicol. Inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. |
Function | 1. To pig pleurisy, streptococcus, attach red filaments, day 2, diarrhea effects; 2. To chickens of contagion rhinitis, pig, ox lung phytophthora duck; 3. Espiratory infection, inflammation, RuXianYan serous disease such as effects; 4. The aquatic product categories: for bacterial enteritis sepsis, disease, red skin disease, vibrio disease, perpendicular scale disease, class nodules disease, Enoch concurrent salmonellosis, scabies disease, eel red eosinophilic disease and bullfrogs bacterial dysentery effects. |
Florfenicol Chemical Properties | |
Melting point | 153 °C |
Boiling point | 618℃ |
density | 1.451±0.06 g/cm3(Predicted) |
alpha | 26 +17.9° (DMF) |
pKa | 10.73±0.46(Predicted) |
RTECS | DB6034000 |
Fp | >110°(230°F) |
storage temp. | 0-6°C |
solubility | Soluble in ethanol to 25mM and in DMSO to 100mM |
form | powder |