| Clarithromycin Basic information | |
| Product Name: | Clarithromycin |
| Synonyms: | 6 – (4 – DIMETHYLAMINO – 3 – HYDROXY – 6 – METHYLTETRAHYDROPYRAN – 2 – YL – foxy) – 14 – baton rouge – 12, 13 – DIHYDROXY – 4 – (5 – HYDROXY); A-56268; 6-O-Methylerythromycin,Erythromycin,6-O-methyl-; ERYTHROMYCIN,6-0-METHYL-6-0-METHYLERYTHROMYCIN/CLARITHROMYCIN |
| CAS: | 81103-11-9 |
| MF: | C38H69NO13 |
| MW: | 747.95 |
| EINECS: | 1806241-263-5 |
| Product Categories: | Macrocyclic lactam antibiotics; Active pharmaceutical ingredients. Amino acid; Pharmaceutical intermediate; Antibiotic drugs; Macrolide antibiotics; Pharmaceutical raw materials; Drugs; Microbial metabolites; Antibiotics; Small molecule inhibitor; Resistance to infection; Food additives; Pharmaceutical, pesticide and dye intermediates; Chemical reagents; Active drug intermediate; General biochemical reagent-antibiotics; Veterinary drug raw materials; Biological reagents; industrialization |
| Introduction | Clarithromycin, also known as methyxithromycin, is a derivative of erythromycin, which is a macrocyclic lipid antibiotic.
White crystalline powder or colorless needle crystal, odorless, bitter taste. More soluble in chloroform or acetone, slightly soluble in ethanol, ether or methanol, almost insoluble in water. Clarithromycin is an antibiotic with a wide antimicrobial spectrum. |
| Application | Is a derivative of erythromycin, a macrocyclic lipid antibiotic, mainly used for diseases caused by bacterial infection, including lower respiratory tract infections, such as bronchitis and pneumonia; For upper respiratory tract infections, such as pharyngitis and sinusitis; It can also be used for skin and soft tissue infections, such as folliculitis, cellulitis, erysipelas, etc. It can also be used for local infection, disseminated infection and mixed infection. Clarithromycin can be combined with other drugs to eradicate Helicobacter pylori infection. It can also be used in odontogenic infections, so clarithromycin is an antibiotic with a broad antimicrobial spectrum. |
| Clarithromycin Chemical Properties | |
| Melting point | 217-220°C |
| Boiling point | 86℃ |
| Density | 1.1334 (rough estimate) |
| flash point | >110°(230°F) |
| specific rotation | D24 -90.4° (c = 1 in CHCl3) |
| Refractive index | -92 ° (C=1, CHCl3) |
| Storage condition | -20°C |
| Solubility | Soluble in DMSO |
| form | Powder. |
| color | White crystalline powder or colorless needle-like crystal |
| pKa | pKa 8.99(H2O t=25.0 I=0.167) (Uncertain) |
