| Ketoconazole Basic information | |
| Product Name: | Ketoconazole |
| Synonyms: | 3-dioxolan-4-yl)methoxy)phenyl)-,cis-;fungarest;fungoral;ketoconazol;ketoderm;ketoisdin;kw-1414;nizoral |
| CAS: | 65277-42-1 |
| MF: | C26H28Cl2N4O4 |
| MW: | 531.43 |
| EINECS: | 265-667-4 |
| Product Categories: | Antifungal drugs; Imidazole; Pharmaceutical raw materials; Antifungal agents; It’s an antifungal drug. Used to treat conditions such as beriberi and excessive dandruff; Antibiotics; Pharmaceutical raw materials; Pharmaceutical and chemical industry; Cosmetic raw materials; Antipyretic and analgesic; Small molecule inhibitor; Antiviral and anti-infective class; Raw materials for skin application; Skin antibacterial; Pharmaceutical and chemical industry; Medicinal raw materials; Chemical raw materials; Inorganic chemical raw materials; Organic raw materials; Metabolism; Antifungal; Antibacterial; Imidazole broad-spectrum antifungal agents; Pharmaceutical imidazole broad-spectrum antifungal drugs; Skin antibacterial raw materials; Veterinary medicine; Hair care series; Synthetic antimicrobial agents; Chemical intermediates; Antiviral intermediate; Additive; industrialization |
| Application | Ketoconazole is an imidazole broad-spectrum antifungal agent.
It is an antifungal drug used to treat beriberi and excessive dandruff. A broad-spectrum antifungal agent, it is a CYP3A4 inhibitor. |
| Ketoconazole Chemical Properties | |
| Melting point | 148-152 °C |
| Boiling point | 753.4±60.0 °C(Predicted) |
| Density | 1.4046 (rough estimate) |
| flash point | 9℃ |
| optical activity | [α]20/D -1 to 1°, c = 4 in methanol |
| Refractive index | -10.5 ° (C=0.4, CHCl3) |
| Storage condition | 2-8°C |
| Solubility | methanol: soluble50mg/mL |
| form | Powder. |
| color | white to light yellow |
| pKa | pKa 3.25/6.22(H2O,t =25,I=0.025) (Uncertain) |
